No shortage to fear for monkeypox vaccine

The only laboratory to manufacture a vaccine already approved specifically against monkeypox, the Danish Bavarian Nordic saw orders soar with the outbreak of the virus, but ensures that it can honor them all.

“The approval (from the American health authorities) received in 2019 (…) suddenly became very, very relevant for international health”, smiles, at the headquarters of the biotech in the port of Copenhagen, its vice-president Rolf Sass Sørensen.

A new pandemic?

Surprised by the spread of the disease outside the eleven countries of West and Central Africa where it is endemic, Mr. Sass Sørensen nevertheless assures that he can meet demand, even with a single production plant.

“With the current demand, we can easily supply the global market. We have a few million doses in bulk, we can bottle them and ensure the current outbreak is dealt with,” he explains.

Several million doses

Bavarian Nordic has an annual production capacity of 30 million doses at its factory north of the Nordic capital.

Its smallpox vaccine is a 3rd generation serum, i.e. a non-replicating live vaccine (which does not replicate in the human body), marketed under the name Imvanex in Europe where it has been authorized since 2013, from Jynneos in the United States. United and Imvamune in Canada.

Stocks as far as Europe

First indicated against smallpox in adults, a disease considered eradicated for about forty years, the treatment requires two doses.

According to Mr Sass Sørensen, the vaccine is “in stock in many countries” and it can be applied before or after being exposed to the disease. “If you are vaccinated a few days after being exposed, you can also be protected,” he points out.

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After getting the green light from US authorities three years ago, Bavarian Nordic is working to extend its European registration for monkeypox. First deliveries are expected by the end of June for priority countries, European authorities said.

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