Key Changes to the World Anti-Doping Agency’s Prohibited Substances List
The World Anti-Doping Agency (WADA) has introduced significant updates to its list of prohibited substances, effective January 1. One notable addition is the opioid fentanyl, which is now banned out of competition. Fentanyl, a potent analgesic, can lead to addiction with prolonged use and falls under the category of ‘substances of abuse’ alongside tramadol.
Expanded List of Prohibited Substances
The 2025 WADA list includes several new substances that affect muscle function, hormones, and metabolic modulators. These additions mimic the action of insulin and modulate mitochondrial activity. Furthermore, the list of prohibited diuretics and masking agents now includes xipamide, while guanfacine has been removed. Hydrafinil, a stimulant no longer authorized for medical use, has also been added to the list.
Permitted Forms of Use and Exceptions
WADA has also determined new permitted forms of use for the asthma medication formoterol. Additionally, blood donation is now allowed, but only in accredited centers. The use of beta blockers in skiing and snowboarding has also been permitted.
Consequences of Non-Compliance
All individuals involved in the world of sports are required to be aware of and respect these regulations. Failure to do so can result in severe consequences, as seen in the ‘Sharapova case’ in 2016. The tennis player was sanctioned for using Meldonium, which was authorized until December 31 but prohibited on the new list.